Whilst the series itself isnt based on a true story, its based on the book of the same name by John Marrs, there have been scientists in the past who have tried to launch similar scientific breakthroughs.
Can the show the one be real?
Though the show is based on the book of the same name by John Marrs and is completely fictional, you may be wondering whether DNA matching is possible in real life. Some examples are DNA Romance, Gene Partner, and a startup called Pheramor. (Pheramor has gone out of business, according to this report.)
Is DNA match making real?
Basically, yes, DNA-based dating does exist however, its no where near as extensive and legitimate as The Ones take on the concept. If you sift through the internet, there are many dating websites that claim to use genetics in order to match potential romantic partners, one example being, SingledOut.