Weight loss pills, like many fat burners or thermogenics, work in a variety of ways; some increase your body’s baseline metabolic rate, others fill you up and tamp down on your feelings of hunger, so you consume less food, while others block or slow the absorption of the food you do eat. It’s a complicated series of mechanisms that govern how your body gains or loses weight Click here for the lowest price on Amazon. MELT is a well-balanced and fairly simple combination of a small number of effective weight loss supplements Low-end weight loss pills may not have the appropriate dosage of their ingredients, but with a top-rated weight loss pill, you can just follow the recommended dosage on the bottle. Recap.
512 Shares There are probably more weight loss pills on the market than pounds that need to be shed. Okay, that’s obviously an exaggeration, but you get my drift. Even with reviews, it can be really hard to sort through the good and bad supplements out there today. They usually work in one of three ways: • Suppress your appetite • Increase how much fat you burn • Reduce absorption of fat A good diet and healthy lifestyle choices are necessary to lose weight, but there’s nothing wrong with taking a to help you reach your goals faster.
The problem is that there are so many, it’s hard to figure out which one to choose! Weight loss pills and supplements are big business, with over 36 billion dollars sold annually, and an average growth rate of a billion dollars a year.
() This gives vendors lots of incentive to sell products, and there are poor quality supplements out there that don’t work, and can even make you sick! We’re getting rid of the guesswork by checking out some of the best-selling weight loss pills on the market and finding the research to see if their claims aren’t just heady sales pitches.
Here are the top 7 best-selling weight loss pills. Let’s find out which pills work based on both science and testimonials.
• is conjugated linoleic acid, an omega 6 fatty acid that occurs naturally in , eggs, beef, and lamb. I know it seems counter-intuitive to use a fat to lose fat, but a growing number of dieters swear by it. Not only is it reported to help you lose weight, but when used alongside exercise and a , it increases strength and endurance.
Sounds too good to be true, right? In the late 80s, researchers discovered CLA and its ability to reduce body fat, and a number of studies were done to test their results out.
A review of over 200 studies found that not only does it help with weight loss and endurance, but it’s great for the immune system. () It can keep fat cells small and break down the ones you already have, so you don’t put on weight.
The jury is out scientifically about whether it helps build muscle mass, but there’s plenty of anecdotal evidence from happy customers to support that claim.
is derived from safflower oil, non-GMO, free of gluten, soy, egg, and dairy, and has 1000mg of active CLA. 90% of users from across markets have found it useful for losing weight with few side-effects.
A cautionary note, though; fatty acids can sometimes give you some nausea or diarrhea, and CLA 1250 is no different. • is a fruit called tamarind that grows in India and Southeast Asia. The key ingredient that is supposed to help with weight loss is , a well-studied appetite suppressant and fat burner. You can find it as the latest, greatest weight loss supplement, and many companies claim that it makes you want to eat less, improves mood, and increases energy, which makes you want to work out more.
Studies are a mixed bag with this one. Some find a significant reduction in fat in participants, while others only saw a small, statistically insignificant reduction in weight.
() They also found little use for it as an appetite suppressant. () People love this stuff, though, and they often get great results, so what could be causing their weight loss? Researchers believe that it might be because increases the production of , the “feel good” chemical in your brain that makes you calm and happy.
The happier you are, the less you want to eat and crave comfort foods. It also helps control blood sugar levels, which can be responsible for sugary food cravings. The main problem with garcinia cambogia is that it has some common side-effects, like headaches, nausea, dizziness, and lowering immune system function. It also can’t be used by people with high blood pressure, liver or kidney issues, diabetics, and many other conditions.
Potent Organics is gluten-free and vegan, and 69% of people who use it report that it helped them lose weight. • The advertising around being a fat burning miracle have reached epic proportions, ever since a popular television doctor discussed it on his show. People report losing as much as but the myths might be a whale tale.
There have only been a couple of studies to find out whether this compound derived from a type of plant really works to help lose weight. What they found isn’t what you would expect. There were two separate studies done; one for men and one for women.
The men in the study saw a significant decrease in fat mass, while the women didn’t. () () Researchers haven’t been able to figure out why the men saw a decrease in fat and the women didn’t, but in both cases, fat didn’t melt away like the claims say.
They do believe, though, that it works because it prevents additional weight gain. by Bio Schwartz is a popular weight loss supplement that is non-GMO, and free of gluten and allergens.
They also claim to be formulated by a physician and third-party tested. • is the only over-the-counter weight loss drug that’s been approved by the FDA, but does it really help you shed pounds? , the drug in Alli, works by inhibiting the amount of fat your body absorbs.
It removes about 25% of the fat from the food that you eat, which is why the manufacturers suggest that you eat a low-fat diet while you’re on it. A study that followed 100,000 orlistat users and found that they lost about two pounds a month on average, but over the long-term, they couldn’t keep it off. () Alli has a bit of a nasty side-effect; if you eat too much fat while you’re taking it, it can cause oily, loose stool that can force a mad dash to the toilet.
It can also cause gas and intestinal pain. Other than that, is generally considered safe, but there are a bunch of precautions, so if you want to take it, check with your doctor first. • Raspberries are not only yummy, they contain a natural chemical called that can help you lose weight!
The problem is that it’s one of the most expensive weight loss supplements out there, so many manufacturers use a synthetic version of it. While there have been lots of studies on rats that show that increase , there hasn’t been one study on humans yet, so the jury is still out. A study on rats did show that it increased adiponectin, a hormone that regulates metabolism in the body. () Another study showed that when ketone is mixed with capsaicin, ginger, garlic, and caffeine, a group of women had significant weight loss and reduction in body fat.
() It’s also safe, and there are many stories from people who absolutely love it, so it won’t hurt to give it a try. by Naturewise uses pure, natural raspberry ketone, and adds acai berry, green tea, cayenne pepper, and African mango seed into a proprietary blend that is gluten-free, vegan, and allergen-free.
• You’ve probably heard that but green coffee beans? It’s another popular weight loss supplement that’s been touted by TV physicians as a super fat buster. A study in 2008 found that green coffee extract contains three types of acids that are antioxidant and can help with weight loss. () Many also contain about as much caffeine as black coffee, so they’re considered a stimulant.
Stimulants, as you know, can give you a nice boost of energy, which can make you want to run on the treadmill a little longer. Numerous studies also show that the form of chlorogenic acid it contains is easily absorbed, which helps it burn glucose and stored fat.
NatureWise has low levels of caffeine in it, so it won’t give you the jitters. It’s also vegan, gluten-free, and doctor formulated. • Why buy garcinia cambogia extract, green coffee bean extract, and CLA on their own, when you can get them all in ?
It also includes L- carnitine, another popular supplement. We’ve discussed these ingredients here, so you already know how effective they are. Buyers found that the combination in is a great way to shed a few pounds without getting the stimulant shakes.
It’s also gluten-free, which is always a plus! Weight Loss Dieting Remember that when it comes to weight loss, dieting is always the most important factor driving your results. The supplements above should be added to a weight loss diet plan for maximum results. Our #1 recommended weight loss plan, the , will help you shed 10-21 pounds in just 21 days! It’s designed to help you break bad eating habits, develop new relationships with healthy foods, and maintain weight loss beyond the diet.
We have clients over 200 pounds that have lost 70, 80, and 90+ pounds on our diet! If you enjoyed this article on weight loss pills or have any questions, please feel free to leave a comment below!
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There are many different weight loss solutions out there. This includes all sorts of pills, drugs and natural supplements. These are claimed to help you lose weight, or at least make it easier to lose weight combined with other methods. They tend to work via one or more of these mechanisms: • Reduce appetite, making you feel more full so that you eat fewer calories • Reduce absorption of nutrients like fat, making you take in fewer calories • Increase fat burning, making you burn more calories Here are the 12 most popular weight loss pills and supplements, reviewed by science.
became popular worldwide after being featured on the Dr. Oz show in 2012. It is a small, green fruit, shaped like a pumpkin. The skin of the fruit contains hydroxycitric acid (HCA).
This is the active ingredient in garcinia cambogia extract, which is marketed as a diet pill. How it works: Animal studies show that it can inhibit a fat-producing enzyme in the body and increase levels of serotonin, potentially helping to reduce cravings (, ). Effectiveness: One study with 130 people compared garcinia against a dummy pill.
There was no difference in weight or body fat percentage between groups (). A 2011 review that looked at 12 studies on garcinia cambogia found that, on average, it caused weight loss of about 2 pounds (0.88 kg) over several weeks ().
Side effects: There are no reports of serious side effects, but some reports of mild digestive problems. Bottom Line: Even though garcinia cambogia may cause modest weight loss, the effects are so small that they probably won’t even be noticeable. has been around for more than a decade, and is currently one of the most popular weight loss supplements in the world. There are several different types, but the most common one is simply called "Hydroxycut." How it works: It contains several ingredients that are claimed to help with weight loss, including caffeine and a few plant extracts.
Effectiveness: One study showed that it caused 21 lbs (9.5 kg) of weight loss over a 3 month period (). Side effects: If you are caffeine sensitive, you may experience anxiety, jitteriness, tremors, nausea, diarrhea and irritability. Bottom Line: Unfortunately, there is only one study on this supplement and no data on long-term effectiveness. More research is needed. is the most commonly consumed psychoactive substance in the world ().
It is found naturally in , green tea and , and added to many processed foods and beverages. Caffeine is a well known , and is often added to commercial weight loss supplements. How it works: Short-term studies have shown that caffeine can boost metabolism by 3-11%, and increase fat burning by up to 29% (, , , ).
Effectiveness: There are also some studies showing that caffeine can cause modest weight loss in humans (, ).
Side effects: In some people, high amounts of caffeine can cause anxiety, insomnia, jitteriness, irritability, nausea, diarrhea and other symptoms. Caffeine is also addictive and can reduce the quality of your sleep. There really is no need to take a supplement or a pill with caffeine in it.
The best sources are quality coffee and green tea, which also have and other health benefits. Bottom Line: Caffeine can boost metabolism and enhance fat burning in the short term. However, a tolerance to the effects may develop quickly. Orlistat is a pharmaceutical drug, sold over-the-counter under the name , and under prescription as Xenical.
How it works: This weight loss pill works by inhibiting the breakdown of fat in the gut, making you take in fewer from fat. Effectiveness: According to a big review of 11 studies, orlistat can increase weight loss by 6 pounds (2.7 kg) compared to a dummy pill (). Other benefits: Orlistat has been shown to reduce blood pressure slightly, and reduced the risk of developing type 2 diabetes by 37% in one study (, ).
Side effects: This drug has many digestive , including loose, oily stools, flatulence, frequent bowel movements that are hard to control, and others. It may also contribute to deficiency in fat-soluble vitamins, such as vitamins A, D, E and K.
It is usually recommended to follow a while taking orlistat, in order to minimize side effects. Interestingly, (without drugs) has been shown to be as effective as both orlistat and a low-fat diet combined (). Bottom Line: Orlistat, also known as Alli or Xenical, can reduce the amount of fat you absorb from the diet and help you lose weight.
It has many side effects, some of which are highly unpleasant. Raspberry ketone is a substance found in raspberries, which is responsible for their distinct smell. A synthetic version of is sold as a weight loss supplement. How it works: In isolated fat cells from rats, raspberry ketones increase breakdown of fat and increase levels of a hormone called adiponectin, believed to be related to weight loss ().
Effectiveness: There is not a single study on raspberry ketones in humans, but one rat study using massive doses showed that they reduced weight gain (). Side effects: They may cause your burps to smell like raspberries. Bottom Line: There is no evidence that raspberry ketones cause weight loss in humans, and the rat studies showing it to work used massive doses.
are simply normal coffee beans that haven't been roasted. They contain two substances believed to help with weight loss, caffeine and chlorogenic acid. How it works: Caffeine can increase fat burning, and chlorogenic acid can slow the breakdown of in the gut. Effectiveness: Several human studies have shown that green coffee bean extract can help people lose weight (, ). A review of 3 studies found that the supplement made people lose 5.4 more pounds (2.5 kg) than placebo, a dummy pill ().
Other benefits: Green coffee bean extract may help lower blood sugar levels, and reduce blood pressure. It is also high in antioxidants (, , , ). Side effects: It can cause the same side effects as caffeine.
The chlorogenic acid in it may also cause diarrhea, and some people may be allergic to green coffee beans (). Bottom Line: Green coffee bean extract may cause modest weight loss, but keep in mind that many of the studies were industry sponsored.
is a type of fiber found in the roots of the elephant yam, also called konjac. How it works: Glucomannan absorbs water and becomes gel-like. It "sits" in your gut and promotes a feeling of fullness, helping you eat fewer calories (). Effectiveness: Three human studies showed that glucomannan, combined with a healthy diet, can help people lose 8-10 pounds (3.6-4.5 kg) of weight in 5 weeks (). Other benefits: Glucomannan is a fiber that can feed the friendly bacteria in the intestine.
It can also lower blood sugar, blood cholesterol and triglycerides, and is very effective against constipation (, , ). Side effects: It can cause bloating, flatulence and soft stools, and can interfere with some oral medications if taken at the same time. It is important to take glucomannan about a half an hour before meals, with a glass of water. If you would like to try it, has a good selection available. You can find an . Bottom Line: Studies consistently show that the fiber glucomannan, when combined with a healthy diet, can help people lose weight.
It also leads to improvements in various health markers. is a relative newcomer on the diet pill market. It is a combination of two plant extracts that may change the metabolism of fat cells.
How it works: It is claimed to make it harder for fat cells to multiply, decrease the amount of fat that they pick up from the bloodstream, and help them burn stored fat. Effectiveness: So far, only one study has been done on Meratrim. A total of 100 obese people were placed on a strict 2000 calorie diet, with either Meratrim or a dummy pill ().
After 8 weeks, the Meratrim group had lost 11 pounds (5.2 kg) of weight and 4.7 inches (11.9 cm) off their waistlines. They also had improved quality of life and reduced blood sugar, cholesterol and triglycerides. Side effects: No side effects have been reported. For a detailed review of Meratrim, . Bottom Line: One study showed that Meratrim caused weight loss and had a number of other health benefits.
However, the study was industry sponsored and more research is needed. Green tea extract is a popular ingredient in many weight loss supplements. This is because have shown the main antioxidant in it, EGCG, to aid fat burning.
How it works: Green tea extract is believed to increase the activity of norepinephrine, a hormone that helps you burn fat (). Effectiveness: Many human studies have shown that green tea extract can increase fat burning and cause fat loss, especially (, , , ). Side effects: Green tea extract is generally well tolerated. It does contain some caffeine, and may cause symptoms in people who are caffeine sensitive. Additionally, all of the should apply to as well. Bottom Line: Green tea and green tea extract can increase fat burning slightly, and may help you lose belly fat.
, or CLA, has been a popular fat loss supplement for years. It is one of the "healthier" trans fats, and is found naturally in some fatty animal foods like and . How it works: CLA may reduce appetite, and stimulate the breakdown of body fat (, ). Effectiveness: In a major review of 18 different studies, CLA caused weight loss of about 0.2 pounds (0.1 kg) per week, for up to 6 months (). According to another review study from 2012, CLA can make you lose about 3 lbs (1.3 kg) of weight, compared to a dummy pill ().
Side effects: CLA can cause various digestive side effects, and may have harmful effects over the long term, potentially contributing to fatty liver, insulin resistance and increased inflammation. Bottom Line: CLA is an effective weight loss supplement, but it may have harmful effects over the long term.
The small amount of weight loss is not worth the risk. is an extract from a plant in the mint family, claimed to be effective for losing weight.
How it works: It is believed to raise levels of a compound inside cells called cAMP, which may stimulate fat burning ().
Effectiveness: One study in 30 overweight and obese men showed that forskolin reduced body fat and increased muscle mass, while having no effect on body weight. Another study in 23 overweight women found no effects (, ). Side effects: There is very limited data on the safety of this supplement, or the risk of side effects.
Bottom Line: The two small studies on forskolin have shown conflicting results. It is best to avoid this supplement until more research is done. A type of called bitter orange contains the compound . Synephrine is related to ephedrine, which used to be a popular ingredient in various weight loss pill formulations.
However, ephedrine has since been banned as a weight loss ingredient by the FDA because of serious side effects. How it works: Synephrine shares similar mechanisms with ephedrine, but is less potent. It can and significantly increase fat burning (). Effectiveness: Very few studies have been done on synephrine, but ephedrine has been shown to cause significant short-term weight loss in many studies ().
Side effects: Like ephedrine, synephrine may have serious side effects related to the heart. It may also be addictive. Bottom Line: Synephrine is a fairly potent stimulant, and probably effective for weight loss in the short term. However, the side effects can be serious, so this should only be used with extreme caution. Additionally, there are many prescription weight loss pills that have been shown to be effective.
The most common ones are , , Phentermine and . According to a recent 2014 review study, even prescription weight loss pills don't work as well as you would hope. On average, they may help you lose up to 3-9% of body weight compared to a dummy pill ().
Keep in mind that this is only when combined with a healthy . They are ineffective on their own, and hardly a solution to obesity. Not to mention their many side effects. Out of the 12, these are the clear winners, with the strongest evidence to back them up: • Weight loss: Glucomannan, CLA and Orlistat (Alli) • Increased fat burning: and green tea extract However, I have to advise against Orlistat due to the unpleasant side effects, and against CLA due to the harmful effects on metabolic health.
That leaves us with glucomannan, green tea extract and caffeine. These supplements can be useful, but the effects are modest at best.
Unfortunately, NO supplement or pill really works that well for weight loss. They may give your metabolism a bit of a nudge and help you lose a few pounds, but that's where it ends, unfortunately. and are still the best ways to lose weight, and work better than all the diet pills combined. Healthline and our partners may receive a portion of the revenues if you make a purchase using a link above.
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